VitaPep Serum+ TB-500 Topical Serum — 1.2 mg / 30 mL

TB-500 Topical Serum, Ready to Apply

VitaPep Serum+ is a ready-to-use, 30 mL topical cosmetic formula containing 1.2 mg of TB-500. It combines the TB-500 peptide fragment with a 70% DMSO and 30% deionized-water carrier and is available with a serum pump or 1 mL dropper.

There is no powder to mix and no reconstitution step. The product is designed for measured external application, while VitaPep’s published batch records let you review the peptide-content and quality testing associated with the identified sample.

Quick Facts

Why Choose VitaPep Serum+ TB-500 Topical Serum?

• Ready to use: The serum arrives prepared for topical application, with no mixing or reconstitution required.
• Designed for direct application: Apply the serum to the intended external area according to the current product directions.
• Choose your applicator: Select a serum pump for convenient, repeatable application or a 1 mL dropper for visible volume markings.
• Clearly stated formula: VitaPep discloses the bottle volume, peptide amount, TB-500 fragment identity, and DMSO/water composition.
• Batch-specific transparency: Published documentation separates peptide-content testing from microbiological and heavy-metal testing.

TB-500 and Thymosin Beta-4 Are Not the Same Thing

TB-500 is the synthetic N-acetylated seven-amino-acid fragment corresponding to residues 17–23 of the full 43-amino-acid thymosin beta-4 protein. Its sequence is Ac-LKKTETQ.

The fragment’s identity was characterized in a primary analytical study published in 2012. Sharing a short sequence with thymosin beta-4 does not make TB-500 equivalent to the full-length protein, and research involving full-length thymosin beta-4 should not be presented as proof of what TB-500 does.

What Does TB-500 Research Actually Show?

An FDA scientific review published in 2026 reported that it did not identify human-exposure studies for TB-500 by any route. The review also discussed a 2024 laboratory and animal study in which observed scratch-assay activity was associated with a TB-500 metabolite rather than the parent peptide.

The practical takeaway: Cell, animal, metabolite, or full-length thymosin beta-4 research does not establish that this finished topical cosmetic serum heals tissue, improves recovery, reduces inflammation, or produces another medical outcome in humans.

About the DMSO-Based Carrier

VitaPep Serum+ uses a carrier listed as 70% dimethyl sulfoxide, or DMSO, and 30% deionized water. DMSO is a solvent used as a penetration enhancer in other pharmaceutical and research formulations, as discussed in this peer-reviewed DMSO review.

That general property does not tell us how much TB-500 crosses human skin from this specific finished product. VitaPep therefore identifies the carrier composition without representing the formula as proven transdermal delivery or proven systemic absorption.

For additional context, the official U.S. label for an approved DMSO drug concerns a different concentration, route, and product. It should not be treated as approval or evidence for VitaPep Serum+.

What the Published Testing Shows

• Finished-serum peptide content: Published Janoshik task 44782 identifies VitaPep TB-500 Serum, batch TB020, and reports 0.04 mg/mL of TB-500 in the submitted finished sample. Across 30 mL, that corresponds to the listed 1.2 mg bottle amount.
• Fragment identity: The report identifies the detected compound as the 889 Da TB-500 17–23 fragment rather than full-length thymosin beta-4.
• Measurement context: The report notes a 20% measurement margin because the sample concentration was low.
• Finished-product quality panel: VitaPep separately publishes microbiological and heavy-metal testing for the identified TB020 sample.

Testing results apply only to the submitted sample and batch named in each report. Peptide-content, microbiological, and heavy-metal results document different product characteristics; they do not establish a cosmetic or medical outcome.

View VitaPep’s TB-500 testing documents or check Janoshik task 44782.

How to Use

1. Wash the intended external application area thoroughly.
2. Dry the skin completely before applying the serum.
3. Apply the amount stated on the current product packaging for your selected applicator.
4. Massage the serum gently into the external application area.
5. Allow the area to dry completely before covering it with clothing.
6. Wash your hands thoroughly after application.

Because the formula contains DMSO, apply it only to thoroughly cleaned, fully dry skin. Do not apply over lotions, cosmetics, or other substances. Follow the instructions supplied with your bottle rather than substituting an online pump estimate.

Important Use Information

• For external cosmetic use only.
• Do not inject or ingest.
• Apply only to clean, dry, intact skin.
• Do not apply to broken or irritated skin.
• Avoid contact with eyes and mucous membranes.
• Discontinue use if irritation occurs.
• Keep out of reach of children.
• Review the complete ingredient list, directions, and warnings on the current product label before use.

Competitive athletes: Thymosin beta-4 and its derivatives, including TB-500, appear in section S2 of the 2026 World Anti-Doping Agency Prohibited List. Check the current rules of your governing organization before use.

Learn Before You Choose

See VitaPep’s formulation and testing standards, learn what product testing documents can and cannot tell you, or review how to read topical-serum directions. For general ordering and product questions, visit the VitaPep FAQ.

TB-500 Topical Serum FAQs

What is VitaPep Serum+?

VitaPep Serum+ is a ready-to-use, 30 mL external cosmetic serum containing 1.2 mg of TB-500 in a 70% DMSO and 30% deionized-water carrier.

Is TB-500 the same as thymosin beta-4?

No. TB-500 is the N-acetylated 17–23 fragment of thymosin beta-4, with the sequence Ac-LKKTETQ. It is not the full 43-amino-acid thymosin beta-4 protein.

How much TB-500 is in the bottle?

The listed amount is 1.2 mg per 30 mL bottle. Published finished-batch testing for TB020 reported 0.04 mg/mL in the submitted sample.

What is the carrier formula?

The current formula record lists 70% DMSO and 30% deionized water. General research on DMSO does not establish the degree of peptide delivery or absorption from this finished topical product.

How much should I apply?

Use the application amount stated on the current packaging for your selected applicator. Applicator output can vary, so do not rely on an online estimate from another product or bottle.

Is VitaPep Serum+ injectable?

No. It is formulated and sold for external cosmetic use only. Do not inject or ingest it.

What evidence supports this finished topical formula?

No controlled human evidence for a comparable finished topical TB-500 serum was identified. Research involving full-length thymosin beta-4, animal models, cells, or metabolites does not establish a clinical benefit from this product.

What does “third-party tested” mean here?

VitaPep publishes finished-serum peptide-content testing and a separate microbiological and heavy-metal panel for the identified TB020 sample. Each result applies only to the sample and batch named in its report.